Urinary Tract Infection Research Today is a free monthly online journal that collates and summarizes the latest research about Urinary Tract Infection, including details on uti, causes, prevention, diet, treatment.

Interaction of uropathogenic Escherichia coli with host uroepithelium.

Kau AL, Hunstad DA, Hultgren SJ

Department of Molecular Microbiology, Washington University School of Medicine, 660 S. Euclid Ave., Campus Box 8230, Saint Louis, MO 63110-1093, USA.

Investigation into the pathogenesis of Escherichia coli urinary tract infection has provided numerous insights into the mechanisms by which bacteria adhere, grow and persist in association with host tissue. Many molecular details concerning the interaction of these bacteria with their host have been elucidated, and the murine model of cystitis has generated a new paradigm by which acute and recurrent urinary tract infections may proceed. These advances could potentially result in the development of novel vaccines and therapies for this very costly disease.

Published 7 February 2005 in Curr Opin Microbiol, 8(1): 54-9.
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